Orlando Martins, Sérgio Matos, Maria Helena Figueiredo,Carlos Viegas, Isabel Dias, Teresa Vieira, Pedro Nuno Lopes, Isabel Poiares Baptista and Fernando Guerra
Novel Nanocrystalline Hydroxyapatite for Bone Regeneration
Maxillofacial bone defects resulting from disease or trauma are one main problem for modern dentistry. Regenerative treatments aim to provide the lost initial conditions improving the patient’s life quality. Bone graft substitutes have been regarded as suitable alternatives to obtain regenerative outcomes. Among these, synthetic hydroxyapatites are successfully evaluated bone substitutes, both in pre-clinical as well as clinical studies. The aim of this study is to evaluate the bone regenerative potential of a nanocrystalline hydroxyapatite (nHA), in a delayed healing cranial rabbit model.
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