Zeitschrift für Regenerative Medizin

Case Report: Bell’s Palsy and Stem Cell Therapy

Paul A. Dreschnack, Marvell Scott and Christine Bochenek

Bell’s palsy is the most common form of idiopathic facial paralysis that we see as physicians. We report on a 43-year-old woman with a two-year history of unilateral facial palsy that had stabilized, and was unresponsive to treatment with steroids and antiviral medications. Treatment with adipose-derived mesenchymal stem
cells provided a significant improvement in symptomology with thirty days. Bell’s palsy is an idiopathic facial nerve weakness or palsyof 7th cranial nerve, thought to be caused by a viral or autoimmune origin. It is the most common cause of facial paralysis, accounting for 50-75% of cases and is part of a differential diagnosis of a
cerebrovascular accident. Middle age patients are most commonly affected by the disease process, and it affect both males and females with an equal predilection. Resolution often begins within two weeks, and continues for up to six months. Many, if not most,resolve spontaneously. However, it is not uncommon to see patients
with relentless symptoms for 2-3 years extending to 7-10 years. Comorbid factors contribute to the likelihood of onset, and includepregnancy, diabetes, hypertension, Guillain-Barré syndrome,multiple sclerosis, Lyme Disease and myasthenia gravis, to name a few.