Internationale Zeitschrift für Herz-Kreislauf-Forschung

Near East Acute Coronary Syndromes Percutaneous Coronary Intervention Patients at One Year

Osama Okkeh*, Zakaria Qaqa , Asem Nammas , Ayman Hammoudeh, Raed Al-Awaisheh, Abdelbaset Al-Khatib, Nail Al-Shoubaki, Mohammed Bassam El Tourn, Haidar Farah, Mustafa Al Jammal, Mazen Sidqi , Ibrahim Mofleh Abbadi and Saleh Sebitan

Background: Acute coronary syndrome (ACS) refers to a range of clinical conditions extending from ST-segment elevation myocardial infarction (STEMI) to non–ST-segment elevation myocardial infarction (NSTEMI) and unstable angina. The incidence of ACS became highly common worldwide in patients with coronary arteries disease, especially in patients with other risk factors such as hypercholesterolemia, hypertension, diabetes, and smoking. Percutaneous coronary intervention (PCI) represents a valid treatment option in patients with ACS.

Objectives: The aim of our study was to evaluate the one-year outcomes in patients with ACS undergoing PCI in the Near East region, assess their pharmacological treatments, and to compare the data obtained with the international guidelines.

Methods: This prospective, regional, multicenter, observational study enrolled 162 ACS patients who underwent PCI. The study composed of four visits. Patients were followed up on a span of one year and data regarding risk factors, medical history, medication, antiplatelet treatment, the incidence of hospitalization, and incidences of Major Adverse Cardiac Events (MACE), were collected.

Results: A total of 162 patients were enrolled in this study. Ten patients (7.1%) experienced cardiovascular event within the one year post the PCI procedure. Two patients (1.4%) experienced early stent thrombosis within 30 days of stent implantation. Twelve patients (8.5%) were hospitalized as a result of medical or cardiovascular condition post PCI procedure. The most commonly prescribed postoperative treatments were statins and anti-platelets. Death was experienced in one patient, and the cause of death was unrelated to any cardiovascular disease.

Conclusion: This study demonstrated the effectiveness of PCI procedures in restoring the blood flow in Jordanian patients with ACS. A low number of patients experienced post-procedure hospitalization (8.5%) during the follow-up period. More studies need to be performed to obtain more representative data on patients with ACS in the Near East.