Zeitschrift für Veterinärwissenschaft und medizinische Diagnose

Efficacy of Canine Influenza Virus (H3N8) Vaccine to Reduce Pulmonary Lesions after Co-challenge with Canine Influenza Virus and Streptococcus equi subsp. zooepidemicus

Jamie N Henningson, Laurie J Larson, Marie E Pinkerton, Patricia Sharp, Bliss Thiel, Muralidhar S Deshpande, Tamara Davis, Huchappa Jayappa, Terri L Wasmoen, Nallakannu Lakshmanan and Ronald D Schultz

Efficacy of Canine Influenza Virus (H3N8) Vaccine to Reduce Pulmonary Lesions after Co-challenge with Canine Influenza Virus and Streptococcus equi subsp. zooepidemicus

To examine the effectiveness of canine influenza vaccination to reduce pulmonary lesions in dogs co-challenged with CIV and S. equi subsp. zooepidemicus.In this study, four groups of 7- to 10-week-old, CIV-naive beagles (32 dogs total) were used. One group was vaccinated with CIV vaccine (group 4) and the remaining 3 groups (groups 1, 2 and 3) were not vaccinated. Group 1 was challenged with CIV, group 2 was challenged with S. equi subsp. zooepidemicus and groups 3 and 4 were co-challenged with CIV and S. equi subsp. zooepidemicus.