Zellbiologie: Forschung & Therapie

Isolation and Characterization of Stem Cells Sub Population within the Human Fetal Liver

Shaik Mahaboob Vali, Sandeep Kumar Vishwakarma, Avinash Bardia, Santosh K Tiwari, G.Srinivas, Avinash Raj, Chaturvedula Tripura, Pratibha Nallari, Md. Aejaz Habeeb, Gopal Pande and Aleem A Khan

Isolation and Characterization of Stem Cells Sub Populationwithin the Human Fetal Liver

Human fetal liver is the potential source of both hematopoietic and non-hematopoietic stem cells which can be identified using phenotypic markers. Isolation of homogenous populations of hepatic progenitor cells and their sub-populations is an essential prerequisite for investigating specific markers and appropriate cell types for their possible clinical applications. Several studies have demonstrated the presence of a variety of stem cell populations within the fetal liver. The present study was undertaken to identify specialized cell populations, their valuable growth potential and bi-potential differentiation capability derived from human fetal liver using CD133.