Zeitschrift für Nephrologie und Nierenerkrankungen

The Silent and Progressive Threat of Hypertensive Nephropathy: Risk Factors and Treatment Options

Shigekazu Fumiuara

Hypertensive nephropathy, also known as hypertensive kidney disease, is a condition characterized by kidney damage caused by chronic high blood pressure. Over time, the persistent elevation of blood pressure can lead to structural and functional changes in the kidneys, potentially resulting in kidney failure. Hypertensive nephropathy is a common cause of Chronic Kidney Disease (CKD) and End-Stage Renal Disease (ESRD). The kidneys play a crucial role in regulating blood pressure by controlling fluid balance, electrolytes, and the release of renin, an enzyme involved in blood pressure regulation.